Medical News from MerckMedicus

Todays' [5-7-13]  email from MerckMedicus had an interesting article [below] about how grapes improve heart function. The reaserchers also discuss whether it's the whole grape [ie finger food good for you] or if just a few isolated components do the job [ie fill up that glass of vino]. I don't know if the study was funded by the Table Grape Association or not.

The article's below so you can read it and make your own informed decsion.

Dave Gottlieb, DPM Views above are all mine and no one elses. Neither views above nor below contain views of my employer


Grapes activate genes that reduce high blood pressure related heart failure

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It has been known that grapes are able to reduce heart failure associated with chronic high blood pressure. A US study appearing in the "Journal of Nutritional Biochemistry" has now shown how this effect is achieved: The grapes activate a number of genes that improve the levels of glutathione, the most abundant cellular antioxidant in the heart.

The scientists from the University of Michigan hypertensive, fed heart failure-prone rats a grape-enriched diet for 18 weeks. The results reproduced earlier findings that grape consumption reduced the occurrence of heart muscle enlargement and fibrosis, and improved the diastolic function of the heart. Furthermore, the mechanism of action was uncovered. Grape intake "turned on" antioxidant defense pathways, increasing the activity of related genes that boost production of glutathione.

In the next phase, which will continue into 2014, E. Mitchell Seymour, the head of the study, aims to further define the mechanisms of grape action, and also look at the impact of whole grape intake compared to individual grape phytonutrients on hypertension-associated heart failure. His hypothesis is that whole grapes will be superior to any individual grape component. "The whole fruit contains hundreds of individual components, which we suspect likely work together to provide a synergistic beneficial effect," reasons Seymour.


  • Comments (3)
  • All joking aside, while grapes are healthy one needs to be concerned when eating non organic grapes. Most grapes are covered in pesticide. I came across an article a few weeks ago how they examined the grape and found 17 different chemicals on and in the grape. I happen to be a big grape eater both red and green and always have them in my house.I haven't yet switched over to organic and I might be killing myself. I just didn't want you all to meet the same fate. I have this disconnect as I don't see the chemical so my brain doesn't internalize how bad it may be. Similiar possibly to the diabetic and the neurotrophic ulcer who just doesn't get it.
  • I prefer my grapes fermented, red (occasionally white, depending on the season of the year), and aged.


  • I guess that's why grape seed extract, a supplement that's been around for quite awhile, has been touted as good for us too.

    But then, what about those "grapes of wrath" ?  Those sound stressful, in which case those would not be so good for the ailing heart.  --Woops, my bad, that's a Steinbeck novel.  (Sorry, couldn't help it... not enough humor, if any, in this forum lately.)



    P.S.  And it's a real bummer us high number entry writers got capped (limited); oh well, the big boss has got to do what he's got to do.