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In chronic wounds, unmanaged bioburden can progress to biofilm, which is challenging and often unresponsive to conventional treatment
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Biofilm can adversely affect tissue repair and delay healing1,2
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Biofilm can re-form within 24 hours following debridement3
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Topical antimicrobials, such as silver, have demonstrated cytotoxic effects associated with delayed healing4,5
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Systemic antibiotics can fail to reach adequate levels in localized tissue6
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Now there is a novel technology to manage bioburden while supporting healing: PuraPly™ Antimicrobial (AM), the first purified collagen matrix with PHMB*7
Provides clinical benefits in 3 ways:
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Purified Type I collagen matrix creates a durable, biocompatible scaffold8
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Effective barrier against a wide range of microorganisms2,8
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PHMB is known to disrupt and inhibit the formation of biofilm on the wound surface2
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| *PHMB = polyhexamethylenebiguanide hydrochloride. |
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Learn how PuraPly™ AM is changing the way some clinicians practice wound care
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| "PuraPly™ AM has changed the way that I deal with wounds. There's nothing else on the market that has a collagen matrix with a strong antimicrobial that has a broad-spectrum effect with no resistance." |
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Adam J. Teichman, DPM
Sacred Heart Hospital
Allentown, PA
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PuraPly™ Antimicrobial (AM): Manage a wide variety of wounds.
Shield against microbes.
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References:
1. Mulder GD, Cavorsi JP, Lee DK. Wounds. 2007;19(7):173-182. 2. Hubner NO, Kramer A. Skin Pharmacol Physiol. 2010;23(suppl):17-27. 3. Wolcott R, Cutting KF, Ruiz JC. Association for the Advancement of Wound Care. Publication No. UKCT-A0021. 2008:12-17. 4. Zou SB, Yoon WY, Han SK, Jeong SH, Cui ZJ, Kim WK. Int Wound J. 2013;10(3):306-312. 5. Storm-Versloot MN, Vos CG, Ubbink DT, Vermeulen H. Cochrane Database Syst Rev. 2010;(3):CD006478. 6.Leaper D, Snyder RJ. Association for the Advancement of Wound Care. Publication No. UKCT-A0021. 2008:5-9. 7. PuraPly Antimicrobial [package insert]. Canton, MA: Organogenesis Inc; 2015. 8. Data on file. Organogenesis Inc.
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©2015 Organogenesis Inc. OI-A1193 09-2015. All rights reserved. PuraPly Antimicrobial and PuraPly are trademarks of Organogenesis Inc. Please see complete prescribing information at www.organogenesis.com. |
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