Update on the Latest Oral Antibiotic for Lower Extremity Infections

Warren S Joseph, DPM, FIDSA

Warren S Joseph, DPM, FIDSA
Consultant, Lower Extremity Infectious Diseases
Adjunct Clinical Professor
Arizona College of Podiatric Medicine
Midwestern University
Glendale, AZ

There is a widespread misconception that antibiotics given intravenously (IV) are somehow “better”, “stronger” or “more effective” than antibiotics given orally. This just is not the case. Oral antibiotics can have similar bioavailability as IVs and be every bit as effective without the cost or risk of having to place a peripheral or central line. They are also far more convenient for the patient and prescriber with no need for sending the patient to an infusion center or hospital to receive the drug. Dr Joseph will review the use of oral antibiotics for serious lower extremity infections with emphasis on the newer oral drugs that are available to the practitioner. 

Learning Objectives:
  1. Define the concept of drug bioavailability and how oral antibiotics can be similar to IV antibiotics.
  2. Illustrate issues with IV antibiotics including access and cost of placing a line and administration.
  3. Discuss oral antibiotics that have been shown to be as effective as IV agents.
  4. Review the use of oral antibiotics in the treatment of serious lower extremity infections in the case of limb salvage.
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